The malaria blood stage antigen PfCyRPA formulated with the TLR-4 agonist adjuvant GLA-SE elicits parasite growth inhibitory antibodies in experimental animals

Abstract Background Plasmodium falciparum cysteine-rich protective antigen (PfCyRPA) is an invasion complex protein essential for erythrocyte invasion. In contrast to several previously clinically tested merozoite vaccine candidate antigens, PfCyRPA is not polymorphic, making it a promising candidat...

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Bibliographic Details

Published in:	Malaria Journal
Main Authors:	Marco Tamborrini, Anja Schäfer, Julia Hauser, Linghui Zou, Daniel H. Paris, Gerd Pluschke
Format:	Article
Language:	English
Published:	BMC 2023-07-01
Online Access:	https://doi.org/10.1186/s12936-023-04638-8