Lycopene attenuates the inflammation and apoptosis in aristolochic acid nephropathy by targeting the Nrf2 antioxidant system

Lycopene (LYC) is a carotenoid, has antioxidant properties. This study investigated whether lycopene attenuates aristolochic acids (AAs) -induced chronic kidney disease. In this experiment, lycopene was used to intervene C57BL/6 mice with renal injury induced by aristolochic acid exposure. The histo...

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Bibliographic Details

Published in:	Redox Biology
Main Authors:	Yu Wang, Zhihui Liu, Jun Ma, Qingyang Xv, Hongxin Gao, Hang Yin, Ge Yan, Xiaowen Jiang, Wenhui Yu
Format:	Article
Language:	English
Published:	Elsevier 2022-11-01
Subjects:	Lycopene Aristolochic acid nephropathy Oxidative stress injury Inflammatory response Apoptosis Nrf2/HO-1 signaling pathway
Online Access:	http://www.sciencedirect.com/science/article/pii/S221323172200266X