Impairment of the nerve growth factor pathway driving amyloid accumulation in cholinergic neurons: the incipit of the Alzheimer′s disease story?

The current idea behind brain pathology is that disease is initiated by mild disturbances of common physiological processes. Overtime, the disruption of the neuronal homeostasis will determine irreversible degeneration and neuronal apoptosis. This could be also true in the case of nerve growth facto...

Full description

Bibliographic Details

Published in:	Neural Regeneration Research
Main Authors:	Viviana Triaca, Pietro Calissano
Format:	Article
Language:	English
Published:	Wolters Kluwer Medknow Publications 2016-01-01
Subjects:	Alzheimer′s disease onset; NGF pathway disturbances; intraneuronal amyloid generation and release; basal forebrain cholinergic neurons
Online Access:	http://www.nrronline.org/article.asp?issn=1673-5374;year=2016;volume=11;issue=10;spage=1553;epage=1556;aulast=Triaca