Inflammatory markers in pregnancy – identifying drivers in four large cohorts

IntroductionAdaptations of the immune system throughout gestation have been proposed as important mechanisms regulating successful pregnancy. Dysregulation of the maternal immune system has been associated with adverse maternal and fetal outcomes. The design and interpretation of human biomarker stu...

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Bibliographic Details

Published in:	Frontiers in Immunology
Main Authors:	Frederieke A. J. Gigase, Anna Suleri, Elena Isaevska, Anna-Sophie Rommel, Myrthe G. B. M. Boekhorst, Olga Dmitrichenko, Hanan El Marroun, Eric A. P. Steegers, Manon H. J. Hillegers, Ryan L. Muetzel, Whitney Lieb, Charlotte A. M. Cecil, Victor J. M. Pop, Michael Breen, Veerle Bergink, Lot D. de Witte
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2025-06-01
Subjects:	pregnancy immunology maternal immune activation inflammatory marker dynamics cohort study intra-individual correlation
Online Access:	https://www.frontiersin.org/articles/10.3389/fimmu.2025.1561798/full