A cytosolic chaperone complexes with dynamic membrane J-proteins and mobilizes a nonenveloped virus out of the endoplasmic reticulum.

Nonenveloped viruses undergo conformational changes that enable them to bind to, disrupt, and penetrate a biological membrane leading to successful infection. We assessed whether cytosolic factors play any role in the endoplasmic reticulum (ER) membrane penetration of the nonenveloped SV40. We find...

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Bibliographic Details

Published in:	PLoS Pathogens
Main Authors:	Christopher Paul Walczak, Madhu Sudhan Ravindran, Takamasa Inoue, Billy Tsai
Format:	Article
Language:	English
Published:	Public Library of Science (PLoS) 2014-03-01
Online Access:	https://journals.plos.org/plospathogens/article/file?id=10.1371/journal.ppat.1004007&type=printable