Incorporating exon–exon junction reads enhances differential splicing detection

Abstract Background RNA sequencing (RNA-seq) is a gold standard technology for studying gene and transcript expression. Different transcripts from the same gene are usually determined by varying combinations of exons within the gene, formed by splicing events. One method of studying differential alt...

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Bibliographic Details

Published in:	BMC Bioinformatics
Main Authors:	Mai T. Pham, Michael J. G. Milevskiy, Jane E. Visvader, Yunshun Chen
Format:	Article
Language:	English
Published:	BMC 2025-07-01
Subjects:	Exon junction Alternative splicing RNA-sequencing
Online Access:	https://doi.org/10.1186/s12859-025-06210-4