Bacterial origins of thymidylate metabolism in Asgard archaea and Eukarya

Asgard archaea include the closest known archaeal relatives of eukaryotes. Here, the authors provide evidence that eukaryotic and Asgard thymidylate synthases (required for DNA synthesis) may have a bacterial origin, and additional lateral transfer of bacterial genes may have shaped the metabolism o...

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Bibliographic Details

Published in:	Nature Communications
Main Authors:	Jonathan Filée, Hubert F. Becker, Lucille Mellottee, Rima Zein Eddine, Zhihui Li, Wenlu Yin, Jean-Christophe Lambry, Ursula Liebl, Hannu Myllykallio
Format:	Article
Language:	English
Published:	Nature Portfolio 2023-02-01
Online Access:	https://doi.org/10.1038/s41467-023-36487-z