Modulation of Epithelial–Mesenchymal Transition Is a Possible Underlying Mechanism for Inducing Chemoresistance in MIA PaCa-2 Cells against Gemcitabine and Paclitaxel

To elucidate the currently unknown molecular mechanisms responsible for the similarity and difference during the acquirement of resistance against gemcitabine (GEM) and paclitaxel (PTX) in patients with pancreatic carcinoma, we examined two-dimensional (2D) and three-dimensional (3D) cultures of par...

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發表在:	Biomedicines
Main Authors:	Hajime Nakamura, Megumi Watanabe, Kohichi Takada, Tatsuya Sato, Fumihito Hikage, Araya Umetsu, Joji Muramatsu, Masato Furuhashi, Hiroshi Ohguro
格式:	Article
語言:	英语
出版:	MDPI AG 2024-05-01
主題:	3D spheroid culture pancreatic ductal carcinoma RNA sequencing ingenuity pathway analysis (IPA) gemcitabine paclitaxel
在線閱讀:	https://www.mdpi.com/2227-9059/12/5/1011