Immune checkpoint inhibitors as mediators for immunosuppression by cancer-associated fibroblasts: A comprehensive review

The tumor microenvironment (TME) is a significant contributor to cancer progression containing complex connections between cellular and chemical components and provides a suitable substrate for tumor growth and development. Growing evidence shows targeting tumor cells while ignoring the surrounding...

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Bibliographic Details

Published in:	Frontiers in Immunology
Main Authors:	Fatemeh Eskandari-Malayeri, Marzieh Rezaei
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2022-10-01
Subjects:	cancer-associated fibroblast inhibitory immune checkpoint tumor microenvironment immune suppression immunotherapy
Online Access:	https://www.frontiersin.org/articles/10.3389/fimmu.2022.996145/full