Liprin‐α1 contributes to oncogenic MAPK signaling by counteracting ERK activity

PTPRF interacting protein alpha 1 (PPFIA1) encodes for liprin‐α1, a member of the leukocyte common antigen–related protein tyrosine phosphatase (LAR‐RPTPs)‐interacting protein family. Liprin‐α1 localizes to adhesive and invasive structures in the periphery of cancer cells, where it modulates migrati...

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Bibliographic Details

Published in:	Molecular Oncology
Main Authors:	Henna Pehkonen, Artemis Filippou, Juho Väänänen, Iida Lindfors, Mira Vänttinen, Philipp Ianevski, Anne Mäkelä, Pauliina Munne, Juha Klefström, Sanna Toppila‐Salmi, Reidar Grénman, Jaana Hagström, Antti A. Mäkitie, Piia‐Riitta Karhemo, Outi Monni
Format:	Article
Language:	English
Published:	Wiley 2024-03-01
Subjects:	drug screen head and neck squamous cell carcinoma liprin‐α1 MEK/ERK inhibitor MEK/ERK signaling pathway RAS
Online Access:	https://doi.org/10.1002/1878-0261.13593