Insights into anti-tumor immunity via the polyomavirus shared across human Merkel cell carcinomas

Understanding and augmenting cancer-specific immunity is impeded by the fact that most tumors are driven by patient-specific mutations that encode unique antigenic epitopes. The shared antigens in virus-driven tumors can help overcome this limitation. Merkel cell carcinoma (MCC) is a particularly in...

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Bibliographic Details

Published in:	Frontiers in Immunology
Main Authors:	Saumya Jani, Candice D. Church, Paul Nghiem
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2023-05-01
Subjects:	Merkel cell carcinoma Merkel cell polyomavirus skin cancer anti-tumor T cells immunotherapy oncoproteins
Online Access:	https://www.frontiersin.org/articles/10.3389/fimmu.2023.1172913/full