Endothelial cells release microvesicles that harbour multivesicular bodies and secrete exosomes

Abstract Extracellular vesicles (EVs) released by endothelial cells support vascular homeostasis. To better understand endothelial cell EV biogenesis, we examined cultured human umbilical vein endothelial cells (HUVECs) prepared by rapid freezing, freeze‐substitution, and serial thin section electro...

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Bibliographic Details

Published in:	Journal of Extracellular Biology
Main Authors:	Jennifer D. Petersen, Elena Mekhedov, Sukhbir Kaur, David D. Roberts, Joshua Zimmerberg
Format:	Article
Language:	English
Published:	Wiley 2023-04-01
Subjects:	electron microscopy endothelial cell exosome Extracellular vesicle intraluminal vesicle microvesicle
Online Access:	https://doi.org/10.1002/jex2.79