PvML1 suppresses bacterial infection by recognizing LPS and regulating AMP expression in shrimp

Toll and Toll-like receptors (TLRs) play essential roles in the innate immunity of Drosophila and mammals. Recent studies have revealed the presence of Toll-mediated immune signaling pathways in shrimp. However, the recognition and activation mechanism of Toll signaling pathways in crustaceans remai...

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Bibliographic Details

Published in:	Frontiers in Immunology
Main Authors:	Yue Wang, Li-Guo Yang, Guang-Peng Feng, Zong-Li Yao, Shou-Hu Li, Jun-Fang Zhou, Wen-Hong Fang, Yi-Hong Chen, Xin-Cang Li
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2022-12-01
Subjects:	Penaeus vannamei MD2-related lipid-recognition (ML) homologs toll signaling pathway antibacterial activity LPS binding activity recognition and activation mechanism
Online Access:	https://www.frontiersin.org/articles/10.3389/fimmu.2022.1088862/full