Dissecting the Regulation of Arachidonic Acid Metabolites by Uncaria rhynchophylla (Miq). Miq. in Spontaneously Hypertensive Rats and the Predictive Target sEH in the Anti-Hypertensive Effect Based on Metabolomics and Molecular Docking

Uncariarhynchophylla (Miq). Miq. (UR), as a traditional Chinese medicine, was employed in treating hypertension as a safe and effective therapy. The pharmacological properties of UR have characteristics of multiple biological targets and multiple functional pathways. Hypertension is related to impai...

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Bibliographic Details

Published in:	Frontiers in Pharmacology
Main Authors:	Lei Gao, Xinqin Kong, Wenyong Wu, Zijin Feng, Haijuan Zhi, Zijia Zhang, Huali Long, Min Lei, Jinjun Hou, Wanying Wu, De-an Guo
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2022-05-01
Subjects:	Uncaria anti-hypertensive arachidonic acid metabolites sEH = soluble epoxide hydrolase EETS metabolomics
Online Access:	https://www.frontiersin.org/articles/10.3389/fphar.2022.909631/full