Live-attenuated PruΔgra72 strain of Toxoplasma gondii induces strong protective immunity against acute and chronic toxoplasmosis in mice

Abstract Background Toxoplasma gondii is an intracellular opportunistic pathogenic protozoan that poses serious threats, particularly in immunocompromised individuals. In the absence of a robust prophylactic measure, the mitigation and management of toxoplasmosis present formidable challenges to pub...

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Bibliographic Details

Published in:	Parasites & Vectors
Main Authors:	Jing Li, Yu Kang, Ze-Xuan Wu, Shu-Feng Yang, Yu-Yang Tian, Xing-Quan Zhu, Xiao-Nan Zheng
Format:	Article
Language:	English
Published:	BMC 2024-09-01
Subjects:	Toxoplasma gondii PruΔgra72 Live-attenuated vaccine Acute and chronic infection Immune responses
Online Access:	https://doi.org/10.1186/s13071-024-06461-9