Environmental enrichment alleviates hyperalgesia by modulating central sensitization in a nitroglycerin-induced chronic migraine model of mice

Abstract Background Chronic migraine (CM) is a debilitating neurofunctional disorder primarily affecting females, characterized by central sensitization. Central sensitization refers to the enhanced response to sensory stimulation, which involves changes in neuronal excitability, synaptic plasticity...

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Bibliographic Details

Published in:	The Journal of Headache and Pain
Main Authors:	Lei Wang, Xiaoming Liu, Chenlu Zhu, Shouyi Wu, Zhilei Li, Lipeng Jing, Zhenchang Zhang, Yuhong Jing, Yonggang Wang
Format:	Article
Language:	English
Published:	BMC 2024-05-01
Subjects:	Chronic migraine Central sensitization Environmental enrichment TNC VGluT1
Online Access:	https://doi.org/10.1186/s10194-024-01779-2