Modulation of natural killer cell exhaustion in the lungs: the key components from lung microenvironment and lung tumor microenvironment

Lung cancer is the leading cause of tumor-induced death worldwide and remains a primary global health concern. In homeostasis, due to its unique structure and physiological function, the lung microenvironment is in a state of immune tolerance and suppression, which is beneficial to tumor development...

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Bibliographic Details

Published in:	Frontiers in Immunology
Main Authors:	Hongxia Zhang, Jian Wang, Fengqi Li
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2023-11-01
Subjects:	natural killer cells hypofunction exhaustion lung microenvironment lung tumor microenvironment
Online Access:	https://www.frontiersin.org/articles/10.3389/fimmu.2023.1286986/full