Identification of modulators of the ALT pathway through a native FISH-based optical screen

Summary: A significant portion of human cancers utilize a recombination-based pathway, alternative lengthening of telomeres (ALT), to extend telomeres. To gain further insights into this pathway, we developed a high-throughput imaging-based screen named TAILS (telomeric ALT in situ localization scre...

詳細記述

書誌詳細
出版年:Cell Reports
主要な著者: Benura Azeroglu, Simran Khurana, Shih-Chun Wang, Gianna M. Tricola, Shalu Sharma, Camille Jubelin, Ylenia Cortolezzis, Gianluca Pegoraro, Kyle M. Miller, Travis H. Stracker, Eros Lazzerini Denchi
フォーマット: 論文
言語:英語
出版事項: Elsevier 2025-01-01
主題:
オンライン・アクセス:http://www.sciencedirect.com/science/article/pii/S2211124724014657