Biogenesis and regulation of the let-7 miRNAs and their functional implications

ABSTRACT The let-7 miRNA was one of the first miRNAs discovered in the nematode, Caenorhabditis elegans, and its biological functions show a high level of evolutionary conservation from the nematode to the human. Unlike in C. elegans, higher animals have multiple isoforms of let-7 miRNAs; these isof...

Full description

Bibliographic Details

Published in:	Protein & Cell
Main Authors:	Hosuk Lee, Sungwook Han, Chang Seob Kwon, Daeyoup Lee
Format:	Article
Language:	English
Published:	Oxford University Press 2015-09-01
Subjects:	miRNA processing miRNA biogenesis let-7 family TUTase LIN28A/B
Online Access:	http://link.springer.com/article/10.1007/s13238-015-0212-y