Molecular and long-term behavioral consequences of neonatal opioid exposure and withdrawal in mice

IntroductionInfants exposed to opioids in utero are at high risk of exhibiting Neonatal Opioid Withdrawal Syndrome (NOWS), a combination of somatic withdrawal symptoms including high pitched crying, sleeplessness, irritability, gastrointestinal distress, and in the worst cases, seizures. The heterog...

Full description

Bibliographic Details

Published in:	Frontiers in Behavioral Neuroscience
Main Authors:	Amelia D. Dunn, Shivon A. Robinson, Chiso Nwokafor, Molly Estill, Julia Ferrante, Li Shen, Crystal O. Lemchi, Jordi Creus-Muncunill, Angie Ramirez, Juliet Mengaziol, Julia K. Brynildsen, Mark Leggas, Jamie Horn, Michelle E. Ehrlich, Julie A. Blendy
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2023-06-01
Subjects:	opioid neonatal withdrawal brain transcriptome mouse behavior
Online Access:	https://www.frontiersin.org/articles/10.3389/fnbeh.2023.1202099/full