Multi-omics reveals Dengzhan Shengmai formulation ameliorates cognitive impairments in D-galactose-induced aging mouse model by regulating CXCL12/CXCR4 and gut microbiota

Dengzhan Shengmai (DZSM), a traditional Chinese medicine formulation, has been administered extensively to elderly individuals with cognitive impairment (CI). However, the underlying mechanisms by which Dengzhan Shengmai improves cognitive impairment remains unknown. This study aimed to elucidate th...

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Bibliographic Details

Published in:	Frontiers in Pharmacology
Main Authors:	Jing-Yi Hou, He Xu, Guang-Zhao Cao, Liang-Liang Tian, Li-Han Wang, Nai-Qiang Zhu, Jing-Jing Zhang, Hong-Jun Yang
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2023-04-01
Subjects:	Dengzhan Shengmai (DZSM) cognitive impairment (CI) aging CXCR4 CXCL12
Online Access:	https://www.frontiersin.org/articles/10.3389/fphar.2023.1175970/full