A multiparametric analysis including single-cell and subcellular feature assessment reveals differential behavior of spheroid cultures on distinct ultra-low attachment plate types

Spheroids have become principal three-dimensional models to study cancer, developmental processes, and drug efficacy. Single-cell analysis techniques have emerged as ideal tools to gauge the complexity of cellular responses in these models. However, the single-cell quantitative assessment based on 3...

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Bibliographic Details

Published in:	Frontiers in Bioengineering and Biotechnology
Main Authors:	Mario Vitacolonna, Roman Bruch, Ane Agaçi, Elina Nürnberg, Tiziana Cesetti, Florian Keller, Francesco Padovani, Simeon Sauer, Kurt M. Schmoller, Markus Reischl, Mathias Hafner, Rüdiger Rudolf
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2024-08-01
Subjects:	CCD-1137Sk cytokeratin-14 CK14 HaCaT HT-29 Involucrin
Online Access:	https://www.frontiersin.org/articles/10.3389/fbioe.2024.1422235/full