Mulberroside A mitigates intervertebral disc degeneration by inhibiting MAPK and modulating Ppar-γ/NF-κB pathways

Abstract Background Intervertebral disc degeneration (IVDD) is a common spine disease with inflammation as its main pathogenesis. Mulberroside A (MA), isolated from herbal medicine, possesses anti-inflammatory characteristics in many diseases. Whereas, there is little exploration of the therapeutic...

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Bibliographic Details
Published in:Journal of Inflammation
Main Authors: Tao Xu, Hongqi Zhao, Xuan Fang, Shanxi Wang, Jian Li, Hua Wu, Weihua Hu, Rui Lu
Format: Article
Language:English
Published: BMC 2024-08-01
Subjects:
Intervertebral disc degeneration
Mulberroside A
Ppar-γ
MAPK
NF-κB
Online Access:https://doi.org/10.1186/s12950-024-00398-7

Internet

https://doi.org/10.1186/s12950-024-00398-7

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