Integrin-Dependent Transient Density Increase in Detergent-Resistant Membrane Rafts in Platelets Activated by Thrombin

Platelet lipid rafts are critical membrane domains for adhesion, aggregation, and clot retraction. Lipid rafts are isolated as a detergent-resistant membrane fraction via sucrose density gradient centrifugation. The platelet detergent-resistant membrane shifted to a higher density on the sucrose den...

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Bibliographic Details

Published in:	Biomedicines
Main Authors:	Keisuke Komatsuya, Masaki Ishikawa, Norihito Kikuchi, Tetsuya Hirabayashi, Ryo Taguchi, Naomasa Yamamoto, Morio Arai, Kohji Kasahara
Format:	Article
Language:	English
Published:	MDPI AG 2023-12-01
Subjects:	lipid rafts detergent-resistant membrane sucrose density gradient phosphatidylserine platelets clot retraction
Online Access:	https://www.mdpi.com/2227-9059/12/1/69