Oncolytic virotherapy in cancer treatment: challenges and optimization prospects

Oncolytic viruses (OVs) are emerging cancer therapeutics that offer a multifaceted therapeutic platform for the benefits of replicating and lysing tumor cells, being engineered to express transgenes, modulating the tumor microenvironment (TME), and having a tolerable safety profile that does not ove...

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Bibliographic Details

Published in:	Frontiers in Immunology
Main Authors:	Lingjuan Chen, Mengsi Zuo, Qin Zhou, Yang Wang
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2023-12-01
Subjects:	oncolytic viruses (OVs) combination therapy antitumor immunity challenges immune checkpoint inhibitor
Online Access:	https://www.frontiersin.org/articles/10.3389/fimmu.2023.1308890/full