Could Reducing Body Fatness Reduce the Risk of Aggressive Prostate Cancer via the Insulin Signalling Pathway? A Systematic Review of the Mechanistic Pathway

Excess body weight is thought to increase the risk of aggressive prostate cancer (PCa), although the biological mechanism is currently unclear. Body fatness is positively associated with a diminished cellular response to insulin and biomarkers of insulin signalling have been positively associated wi...

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Bibliographic Details

Published in:	Metabolites
Main Authors:	Rachel James, Olympia Dimopoulou, Richard M. Martin, Claire M. Perks, Claire Kelly, Louise Mathias, Stefan Brugger, Julian P. T. Higgins, Sarah J. Lewis
Format:	Article
Language:	English
Published:	MDPI AG 2021-10-01
Subjects:	body fatness prostate cancer biomarker insulin insulin signalling mechanisms
Online Access:	https://www.mdpi.com/2218-1989/11/11/726