Toxicities associated with lymphoma-targeting bispecific antibodies—a review

Bispecific antibodies (bsAbs) are an emerging class of directed immunotherapies with established uses in certain hematological malignancies as well as an emerging role in the treatment of solid organ malignancy. These molecules are able to juxtapose T cells (in most cases) with target tumor cells, f...

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Bibliographic Details

Published in:	Frontiers in Medicine
Main Authors:	Christopher Doig, Costas Kleanthes Yannakou
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2025-07-01
Subjects:	BsAb bispecific antibody CRS cytokine release syndrome ICANS immune effector cell-associated neurotoxicity syndrome
Online Access:	https://www.frontiersin.org/articles/10.3389/fmed.2025.1582975/full