miR-221 activates Sox11 to reduce brain injury after intracerebral hemorrhage via inhibiting neuroinflammation

Abstract As a global public health issue, intracerebral hemorrhage (ICH) is characterized by high morbidity and mortality. Brain injury following ICH is composed of primary and secondary injury, with the latter being more severe and resulting in increased apoptosis. Sox11 (sex-determining region Y-r...

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Bibliographic Details

Published in:	Scientific Reports
Main Authors:	Tianyu Liang, Yongchun Liu, Renyang Liu, Xianmei Shen, Mingxia Xu
Format:	Article
Language:	English
Published:	Nature Portfolio 2025-08-01
Subjects:	Sox11 MiR-221 Secondary brain injury Intracerebral hemorrhage Neuroinflammation
Online Access:	https://doi.org/10.1038/s41598-025-15239-7