Metabolic imaging across scales reveals distinct prostate cancer phenotypes

Abstract Hyperpolarised magnetic resonance imaging (HP-13C-MRI) has shown promise as a clinical tool for detecting and characterising prostate cancer. Here we use a range of spatially resolved histological techniques to identify the biological mechanisms underpinning differential [1-13C]lactate labe...

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Bibliographic Details
Published in:Nature Communications
Main Authors: Nikita Sushentsev, Gregory Hamm, Lucy Flint, Daniel Birtles, Aleksandr Zakirov, Jack Richings, Stephanie Ling, Jennifer Y. Tan, Mary A. McLean, Vinay Ayyappan, Ines Horvat Menih, Cara Brodie, Jodi L. Miller, Ian G. Mills, Vincent J. Gnanapragasam, Anne Y. Warren, Simon T. Barry, Richard J. A. Goodwin, Tristan Barrett, Ferdia A. Gallagher
Format: Article
Language:English
Published: Nature Portfolio 2024-07-01
Online Access:https://doi.org/10.1038/s41467-024-50362-5

Internet

https://doi.org/10.1038/s41467-024-50362-5

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