NEK7 induces lactylation in Alzheimer’s disease to promote pyroptosis in BV-2 cells
Abstract Alzheimer’s disease (AD), an age-related neurodegenerative disorder, is characterized by irreversible brain tissue degeneration. The amyloid-β (Aβ) cascade hypothesis stands as the predominant paradigm explaining AD pathogenesis. This study aimed to elucidate the mechanisms underlying Aβ-in...
| Published in: | Molecular Brain |
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| Main Authors: | , |
| Format: | Article |
| Language: | English |
| Published: |
BMC
2024-11-01
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| Subjects: | |
| Online Access: | https://doi.org/10.1186/s13041-024-01156-9 |