Discovering weaker genetic associations guided by known associations

Abstract Background The current understanding of the genetic basis of complex human diseases is that they are caused and affected by many common and rare genetic variants. A considerable number of the disease-associated variants have been identified by Genome Wide Association Studies, however, they...

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Bibliographic Details

Published in:	BMC Medical Genomics
Main Authors:	Haohan Wang, Michael M. Vanyukov, Eric P. Xing, Wei Wu
Format:	Article
Language:	English
Published:	BMC 2020-02-01
Subjects:	Weak association Linear mixed model GWAS
Online Access:	http://link.springer.com/article/10.1186/s12920-020-0667-4