Urine kidney injury molecule-1 predicts subclinical kidney disease among persons living with HIV initiating tenofovir disoproxil fumarate-based ART in Zambia

IntroductionAntiretroviral therapy (ART) increases the life expectancy of persons living with HIV (PLWH), but not without potentially serious adverse effects. Tenofovir disoproxil fumarate (TDF) can cause nephrotoxicity, manifesting as acute kidney injury (AKI) that may persist after treatment disco...

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Bibliographic Details

Published in:	Frontiers in Nephrology
Main Authors:	Freeman W. Chabala, Edward D. Siew, C. William Wester, Alana T. Brennan, Masauso M. Phiri, Michael J. Vinikoor, Sepiso K. Masenga, Muktar H. Aliyu
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2025-01-01
Subjects:	kidney injury molecule-1 neutrophil gelatinase-associated lipocalin acute kidney injury HIV tenofovir disoproxil fumarate-associated nephrotoxicity Zambia
Online Access:	https://www.frontiersin.org/articles/10.3389/fneph.2024.1468409/full