Evolution of CD8⁺ T Cell Receptor (TCR) Engineered Therapies for the Treatment of Cancer

Engineered T cell receptor T (TCR-T) cell therapy has facilitated the generation of increasingly reliable tumor antigen-specific adaptable cellular products for the treatment of human cancer. TCR-T cell therapies were initially focused on targeting shared tumor-associated peptide targets, including...

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Bibliographic Details

Published in:	Cells
Main Authors:	Yimo Sun, Fenge Li, Heather Sonnemann, Kyle R. Jackson, Amjad H. Talukder, Arjun S. Katailiha, Gregory Lizee
Format:	Article
Language:	English
Published:	MDPI AG 2021-09-01
Subjects:	T-cell receptor (TCR) engineered TCR-T cell therapy tumor antigen clinical trials cancer treatment
Online Access:	https://www.mdpi.com/2073-4409/10/9/2379