Therapeutic and Diagnostic Antibodies to CD146: Thirty Years of Research on Its Potential for Detection and Treatment of Tumors

CD146 (MCAM, MUC18, S-Endo1) is a transmembrane glycoprotein belonging to both CAM and mucin families. It exists as different splice variants and is cleaved from the membrane by metalloproteases to generate a soluble form. CD146 is expressed by numerous cancer cells as well as being one of the numer...

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Bibliographic Details

Published in:	Antibodies
Main Authors:	Jimmy Stalin, Marie Nollet, Françoise Dignat-George, Nathalie Bardin, Marcel Blot-Chabaud
Format:	Article
Language:	English
Published:	MDPI AG 2017-11-01
Subjects:	cancer CD146 antibody therapy diagnosis
Online Access:	https://www.mdpi.com/2073-4468/6/4/17