Clinical relevance of pathogenic germline variants in mismatch repair genes in Chinese breast cancer patients

Abstract The prevalence and clinical relevance of pathogenic germline variants in MMR genes have not been investigated in large series of breast cancers. In this study, we screened the germline variants in MMR genes in 8085 consecutive Chinese breast cancer patients, and investigated the MMR/PD-L1 p...

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Bibliographic Details
Published in:npj Breast Cancer
Main Authors: Li Hu, Jie Sun, Zhongwu Li, Ziwei Qu, Yan Liu, Qiting Wan, Jiaming Liu, Xinyun Ding, Fan Zang, Juan Zhang, Lu Yao, Ye Xu, Yin Wang, Yuntao Xie
Format: Article
Language:English
Published: Nature Portfolio 2022-04-01
Online Access:https://doi.org/10.1038/s41523-022-00417-x