Microbiota-derived urolithin A in monoclonal gammopathies and multiple myeloma therapy

Abstract Background Gut microbiota-derived urolithins may influence multiple myeloma (MM) disease progression and treatment. We analyzed urolithins and their associated microbiota in a retrospective cohort of 45 patients with active MM or premalignant disease using mass spectrometry and 16S rRNA gen...

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Bibliographic Details

Published in:	Microbiome
Main Authors:	Alba Rodríguez-García, Raquel Ancos-Pintado, Roberto García-Vicente, Alejandra Ortiz-Ruiz, Andrés Arroyo, Miguel Ángel Navarro, María Luz Morales, Patricia Guevara-Ramirez, Pablo Justo, Nieves López-Muñoz, José Sánchez-Pina, Rafael Alonso, María Victoria Selma, María Dolores Frutos-Lisón, Rocío García-Villalba, Francisco A. Tomás-Barberán, Rosa Ayala, Joaquín Martínez-López, María Linares
Format:	Article
Language:	English
Published:	BMC 2025-02-01
Subjects:	Multiple myeloma Gut microbiota Urolithin Metabolites
Online Access:	https://doi.org/10.1186/s40168-025-02045-6