Mendelian randomization analysis and validation supports MEGF9 and MLLT11 as potential targets for the treatment of varicocele and male infertility

ObjectiveA growing body of research suggests a link between varicocele and male infertility (MI). However, current evidence is mainly based on retrospective studies, which are prone to interference from confounding factors and cannot establish causal relationships. Mendelian randomization (MR) studi...

Full description

Bibliographic Details

Published in:	Frontiers in Endocrinology
Main Authors:	Bin Cai, Dalin Sun, Weimin Deng, Yihan Jin, Hongle Zhao, Dong Xing, Yuanyuan Liu, Baofang Jin
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2024-09-01
Subjects:	varicocele male infertility genetic causal effect Mendelian randomization analysis Bu Shen Huo Xue Prescription
Online Access:	https://www.frontiersin.org/articles/10.3389/fendo.2024.1416384/full