An overview of the past decade of bufalin in the treatment of refractory and drug-resistant cancers: current status, challenges, and future perspectives

Profound progress has been made in cancer treatment in the past three decades. However, drug resistance remains prevalent and a critical challenge. Drug resistance can be attributed to oncogenes mutations, activated defensive mechanisms, ATP-bind cassette transporters overexpression, cancer stem cel...

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Bibliographic Details

Published in:	Frontiers in Pharmacology
Main Authors:	Qingmei Ye, Xin Zhou, Han Ren, Fangxuan Han, Rong Lin, Juan Li
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2023-10-01
Subjects:	refractory cancers drug resistance bufalin overcome mechanisms
Online Access:	https://www.frontiersin.org/articles/10.3389/fphar.2023.1274336/full