CD4⁺CD25⁺FoxP3⁺regulatory T cells suppress cytotoxicity of CD8⁺effector T cells: implications for their capacity to limit inflammatory central nervous system damage at the parenchymal level

<p>Abstract</p> <p>Background</p> <p>CD4⁺CD25⁺forkhead box P3 (FoxP3)⁺regulatory T cells (T reg cells) are known to suppress adaptive immune responses, key control tolerance and autoimmunity.</p&...

Full description

Bibliographic Details

Published in:	Journal of Neuroinflammation
Main Authors:	Göbel Kerstin, Bittner Stefan, Melzer Nico, Pankratz Susann, Dreykluft Angela, Schuhmann Michael K, Meuth Sven G, Wiendl Heinz
Format:	Article
Language:	English
Published:	BMC 2012-02-01
Subjects:	CD4<sup>+ </sup>T regulatory cells CD8 T effector cells CNS parenchyma Cytotoxicity Neuroinflammation
Online Access:	http://www.jneuroinflammation.com/content/9/1/41