Informed interpretation of metagenomic data by StrainPhlAn enables strain retention analyses of the upper airway microbiome

ABSTRACT Shotgun metagenomic sequencing has the potential to provide bacterial strain-level resolution which is of key importance to tackle a host of clinical questions. While bioinformatic tools that achieve strain-level resolution are available, thorough benchmarking is needed to validate their us...

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Bibliographic Details

Published in:	mSystems
Main Authors:	Nadja Mostacci, Tsering Monika Wüthrich, Léa Siegwald, Silas Kieser, Ruth Steinberg, Olga Sakwinska, Philipp Latzin, Insa Korten, Markus Hilty
Format:	Article
Language:	English
Published:	American Society for Microbiology 2023-12-01
Subjects:	respiratory tract metagenomics bacterial culture strain resolution genome analysis
Online Access:	https://journals.asm.org/doi/10.1128/msystems.00724-23