Comparison of Antibodies with Amylase Activity from Cerebrospinal Fluid and Serum of Patients with Multiple Sclerosis.

We have recently shown that IgGs from serum and cerebrospinal fluid (CSF) of MS patients are active in hydrolysis of DNA and myelin basic protein. According to literature data, anti-DNA and anti-MBP abzymes may promote important neuropathologic mechanisms in this chronic inflammatory disorder and in...

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Bibliographic Details

Published in:	PLoS ONE
Main Authors:	Vasilii B Doronin, Taisiya A Parkhomenko, Massimiliano Castellazzi, Edward Cesnik, Valentina N Buneva, Enrico Granieri, Georgy A Nevinsky
Format:	Article
Language:	English
Published:	Public Library of Science (PLoS) 2016-01-01
Online Access:	https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0154688&type=printable