Selective autophagy impedes KSHV entry after recruiting the membrane damage sensor galectin-8 to virus-containing endosomes

Summary: Kaposi sarcoma-associated herpesvirus (KSHV) is an oncogenic γ-herpesvirus. Autophagy during KSHV entry has remained unexplored. We show that LC3 lipidation as a hallmark of autophagy is induced shortly after KSHV entry. LC3 co-localizes with KSHV in amphisomes during entry and loss of LC3...

Full description

Bibliographic Details

Published in:	Cell Reports
Main Authors:	Katarina Wendy Schmidt, Charlotte Montespan, Danielle Thompson, Miriam S. Lucas, Laure-Anne Ligeon, Harald Wodrich, Alexander S. Hahn, Urs F. Greber, Christian Münz
Format:	Article
Language:	English
Published:	Elsevier 2024-12-01
Subjects:	CP: Immunology CP: Microbiology
Online Access:	http://www.sciencedirect.com/science/article/pii/S2211124724013706