The histone chaperone ANP32B regulates chromatin incorporation of the atypical human histone variant macroH2A

Summary: All vertebrate genomes encode for three large histone H2A variants that have an additional metabolite-binding globular macrodomain module, macroH2A. MacroH2A variants impact heterochromatin organization and transcription regulation and establish a barrier for cellular reprogramming. However...

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Bibliographic Details
Published in:Cell Reports
Main Authors: Imke K. Mandemaker, Evelyn Fessler, David Corujo, Christiane Kotthoff, Andreas Wegerer, Clément Rouillon, Marcus Buschbeck, Lucas T. Jae, Francesca Mattiroli, Andreas G. Ladurner
Format: Article
Language:English
Published: Elsevier 2023-10-01
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Online Access:http://www.sciencedirect.com/science/article/pii/S2211124723013128