IL-21-armored B7H3 CAR-iNKT cells exert potent antitumor effects

Summary: CD1d-restricted invariant NKT (iNKT) cells play a critical role in tumor immunity. However, the scarcity and limited persistence restricts their development and clinical application. Here, we demonstrated that iNKT cells could be efficiently expanded using modified cytokines combination fro...

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Bibliographic Details
Published in:iScience
Main Authors: Yilin Liu, Yuanyuan Dang, Chuhan Zhang, Liu Liu, Wenhui Cai, Liantao Li, Lin Fang, Meng Wang, Shunzhe Xu, Gang Wang, Junnian Zheng, Huizhong Li
Format: Article
Language:English
Published: Elsevier 2024-01-01
Subjects:
Immunology
Cell biology
Cancer
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004223026743

Internet

http://www.sciencedirect.com/science/article/pii/S2589004223026743

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