MMP14 from BM-MSCs facilitates progression and Ara-C resistance in acute myeloid leukemia via the JAK/STAT pathway

Abstract Growing evidence underscores the pivotal impact of crosstalk between leukemic stem cells (LSCs) and mesenchymal stromal cells (MSCs) within their niche on leukemia initiation, progression, and therapy response. Although MMP14 plays an important role in inflammation and cancer, the regulatio...

書目詳細資料
發表在:	Experimental Hematology & Oncology
Main Authors:	Jinxian Wu, Xinqi Li, Yin Liu, Guopeng Chen, Ruihang Li, Hongqiang Jiang, Wanyue Yin, Xiqin Tong, Rui Cao, Xianwang Wang, Xiaoyan Liu, Fuling Zhou
格式:	Article
語言:	英语
出版:	BMC 2025-03-01
主題:	Acute myeloid leukemia Mesenchymal stromal cells MMP14 JAK/STAT pathway PGE2
在線閱讀:	https://doi.org/10.1186/s40164-025-00635-6

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