Zinc-Catalyzed Enantioselective [3 + 3] Annulation for Synthesis of Chiral Spiro[indoline-3,4′-thiopyrano[2,3-<i>b</i>]indole] Derivatives

With a dinuclear zinc-ProPhenol complex as a catalyst, an efficient and novel [3 + 3] annulation of indoline-2-thiones and isatylidene malononitriles has been successfully developed via the Brønsted base and Lewis acid cooperative activation model. This practical methodology gives access to a broad...

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Bibliographic Details

Published in:	Molecules
Main Authors:	Tian-Tian Liu, Yu Chen, Guang-Jian Mei, Yuan-Zhao Hua, Shi-Kun Jia, Min-Can Wang
Format:	Article
Language:	English
Published:	MDPI AG 2023-01-01
Subjects:	dinuclear zinc catalyst asymmetric catalytic reaction [3 + 3] annulation indoline-2-thione isatylidene malononitrile
Online Access:	https://www.mdpi.com/1420-3049/28/3/1056