Blockade of Hepatocyte PCSK9 Ameliorates Hepatic Ischemia-Reperfusion Injury by Promoting Pink1-Parkin–Mediated MitophagySummary

Background & Aims: Hepatic ischemia-reperfusion injury is a significant complication of partial hepatic resection and liver transplantation, impacting the prognosis of patients undergoing liver surgery. The protein proprotein convertase subtilisin/kexin type 9 (PCSK9) is primarily synthesize...

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Bibliographic Details

Published in:	Cellular and Molecular Gastroenterology and Hepatology
Main Authors:	Yu Zhang, Ziyi Wang, Chenyang Jia, Wenjie Yu, Xiangdong Li, Nan Xia, Huiling Nie, Likalamu Pascalia Wikana, Minhao Chen, Yong Ni, Sheng Han, Liyong Pu
Format:	Article
Language:	English
Published:	Elsevier 2024-01-01
Subjects:	Hepatic Ischemia-Reperfusion PCSK9 PINK1 Mitophagy STING
Online Access:	http://www.sciencedirect.com/science/article/pii/S2352345X23001662