Inhibition of Gap Junctional Intercellular Communication Upregulates Pluripotency Gene Expression in Endogenous Pluripotent Muse Cells

Gap junctions (GJ) are suggested to support stem cell differentiation. The Muse cells that are applied in clinical trials are non-tumorigenic pluripotent-like endogenous stem cells, can be collected as stage-specific embryonic antigen 3 (SSEA-3+) positive cells from multiple tissues, and show triplo...

Full description

Bibliographic Details

Published in:	Cells
Main Authors:	Khaled Hatabi, Yukari Hirohara, Yoshihiro Kushida, Yasumasa Kuroda, Shohei Wakao, James Trosko, Mari Dezawa
Format:	Article
Language:	English
Published:	MDPI AG 2022-08-01
Subjects:	muse cells pluripotency gap junction inhibition Cx43 YAP
Online Access:	https://www.mdpi.com/2073-4409/11/17/2701