Loss of SETDB1 decompacts the inactive X chromosome in part through reactivation of an enhancer in the IL1RAPL1 gene
Abstract Background The product of dosage compensation in female mammals is the inactive X chromosome (Xi). Xi facultative heterochromatin is organized into two different types, one of which is defined by histone H3 trimethylated at lysine 9 (H3K9me3). The rationale for this study was to assess SET...
| Published in: | Epigenetics & Chromatin |
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| Main Authors: | , |
| Format: | Article |
| Language: | English |
| Published: |
BMC
2018-08-01
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| Subjects: | |
| Online Access: | http://link.springer.com/article/10.1186/s13072-018-0218-9 |