O-Cyclic Phytosphingosine-1-Phosphate Protects against Motor Dysfunctions and Glial Cell Mediated Neuroinflammation in the Parkinson’s Disease Mouse Models

O-cyclic phytosphingosine-1-phosphate (cPS1P) is a novel and chemically synthesized sphingosine metabolite derived from phytosphingosine-1-phosphate (S1P). This study was undertaken to unveil the potential neuroprotective effects of cPS1P on two different mouse models of Parkinson’s disease (PD). Th...

Full description

Bibliographic Details

Published in:	Antioxidants
Main Authors:	Hyeon Jin Lee, Kyonghwan Choe, Jun Sung Park, Amjad Khan, Min Woo Kim, Tae Ju Park, Myeong Ok Kim
Format:	Article
Language:	English
Published:	MDPI AG 2022-10-01
Subjects:	Parkinson’s disease O-cyclic phytosphingosine-1-phosphate motor dysfunction α-synuclein dopaminergic neuron oxidative stress
Online Access:	https://www.mdpi.com/2076-3921/11/11/2107